Although supplications or dua made at any part of Masjid al-Haram is accepted by Allah, there are some special places where Dua is always accepted. Muslims perform their Hajj and Umrah as they want to purify their souls. The connection that one has with Allah during Hajj and Umrah is unbelievable.
Mataf is the place where Tawaf is performed around the Holy Kaaba. It is said that all your supplications are accepted while performing Tawaf in Mataf. Make sure you utilize this time in calling Allah rather than taking selfies and videos.
Multazam is basically an area which is bordered by Hajr-e-Aswad on one side and the door of Kaaba on the other. When you are done with performing Tawaf around the Holy Kaaba, you should come to this point, place your hands there and make dua.
3. Hateem or Hijr Ismail
The Hijr Ismail or Hateem has a great history and the reward for praying in Hateem is equivalent to praying inside the Holy Kaaba. Hatim or the Hijr-Ismail is yet again a Holy place where duas are accepted.
The Hajr-e-Aswad also is known as The Black Stone was brought down from heaven (Jannah) and was presented to Ibrahim (peace be upon him) so that he could place it in the corner of the Kaaba. If you get an opportunity to kiss the black stone, make dua as it is said to be always accepted.
5. Inside the Holy Kaaba
Even though the doors of Holy Kaaba are never opened for the public, yet the officials and the Royals have the opportunity to so inside it. The dua made inside the Holy Kaaba is always accepted.
6. Below Meezab-e-Rehmat
Meezab e Rehmat is a gold spout on the top of the Holy Kaaba between Rukn e Iraqi and Rukn e Shami from where rainwater tumbles onto Hijr Ismail. Water streams down from the top of the Holy Kaaba through Meezab-e-Rehmat and people think about this water to be magical and full of Shifa.
It is also said that every dua and supplication made under Meezab-e-Rehmat is accepted by Allah.
7. Safa and Marwah
The tow hills where the Muslims perform their saee are Safa and Marwah. The Saee is seven runs that are to be made between the hills to honor the mother of Prophet Ismail, Bibi Hajra. It is said that dua made during Saee is never rejected.
The Maqam e Ibrahim is a sacred place inside the Holy Mosque. It is sunnah to offer two Rakah of prayer there. Dua made at Maqam e Ibrahim is said to be accepted.